3D FEM Model of a Human Cochlea and a Cochlear Implant
- 3D finite element method (FEM) models of human cochleae to simulate the voltage distribution in the cochlea when stimulating with a cochlear implant (CI)
- The 3D model can be customized based on landmarks from CBCT imaging data to represent individual patients
- Voltage distributions can be used to study the activation of the auditory nerve by a CI
Auditory Nerve Fiber models
- Phenomenological and physiological models of auditory nerve fibers stimulated acoustically, electrically, or with electric-acoustic stimulation (EAS)
- Neuron models can be coupled to FEM models for realistic current input
Publications
- Nogueira et al., 2016. Validation of a Cochlear Implant Patient-Specific Model of the Voltage Distribution in a Clinical Setting. Front. Bioeng. Biotechnol. 4, 1–16.
- Jürgens et al., 2018. The effects of electrical field spatial spread and some cognitive factors on speech-in-noise performance of individual cochlear implant users - A computer model study. PLoS One 13, e0193842.
- Ashida and Nogueira, 2018. Spike-Conducting Integrate-and-Fire Model. eneuro 5, ENEURO.0112-18.2018.
- Kipping and Nogueira, 2022. A computational model of a single auditory nerve fiber for electric-acoustic stimulation. J. Assoc. Res. Otolaryngol. 23, 835-858. Source code: Zenodo or GitHub.
- Alvarez et al., 2023. A Computational Model to Simulate Spectral Modulation and Speech Perception Experiments of Cochlear Implant Users. Frontiers in Neuroinformatics.
- Kipping et al., 2024. A Computational Model of the Electrically or Acoustically Evoked Compound Action Potential in Cochlear Implant Users with Residual Hearing. IEEE Transactions on Biomedical Engineering (under review). Source code: Zenodo or GitLab.
- Zhang et al., 2025: Evaluating electrophysiological and behavioral measures of neural health in cochlear implant users: a computational simulation study. IEEE Transactions on Biomedical Engineering. Data available: GitLab.
- Alvarez et al., 2025. A computational loudness model for electrical stimulation with cochlear implants.